Which of the following represents a common symptom of opioid overdose?

• A. Pupil dilation
• B. Hyperactivity
• C. Respiratory depression
• D. Severe headache

Answer: (C)

Respiratory depression is a hallmark symptom of opioid overdose. Opioids, which include substances like heroin, morphine, and prescription pain medications, exert their effects primarily on the central nervous system. One of the critical actions of opioids is their ability to depress the respiratory centers in the brain, leading to a significant reduction in the rate and depth of breathing. This can result in hypoxia, where the body does not get enough oxygen, and it can become life-threatening if not addressed promptly.

In addition to respiratory depression, individuals experiencing an opioid overdose may present with other signs such as pinpoint pupils and altered levels of consciousness, but respiratory depression remains the most significant concern due to its potential for fatal outcomes.