What is a sign of stimulant withdrawal?

• A. Increased energy and alertness
• B. Hallucinations and paranoia
• C. Fatigue and depression
• D. Elevated body temperature

Answer: (C)

Fatigue and depression are recognized signs of stimulant withdrawal. When individuals who have been using stimulant drugs, such as cocaine or amphetamines, stop or significantly reduce their use, they often experience a "crash." This is characterized by intense fatigue, an overwhelming sense of lethargy, and feelings of deep sadness or depression.

The withdrawal symptoms arise because stimulants increase the levels of neurotransmitters like dopamine in the brain, causing heightened energy and feelings of euphoria during use. When the drug is removed, the brain must readjust to the absence of these chemicals, leading to the opposite effects: decreased energy and mood disorders.

While elevated body temperature and symptoms such as hallucinations and paranoia may be associated with stimulant use or overdose, they are not typical of withdrawal. Increased energy and alertness, on the other hand, are what one might experience while using stimulants, not when withdrawing from them. Therefore, fatigue and depression are the hallmark signs indicating that the body is reacting to the lack of stimulation caused by stopping the substance.